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Older Adults with High-risk of Obstructive Sleep Apnea Associated with Frailty among Outpatients in a Tertiary Care in Northeast Thailand

Manchumad Manjawong¹, Apichart So-ngern², Panita Limpawattana¹, Kamolthorn Srisuwannakit³, Pongsak Chokkhatiwat³, Natapong Manomaiwong³, Thanison Kamsuanjig³, Chudapha Khammak³

Affiliation : 1 Division of Geriatric Medicine, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 2 Division of Sleep Medicine, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 3 Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

Background: Several pieces of evidence demonstrated poor sleep quality is associated with frailty. However, the present study demonstrates the association between obstructive sleep apnea (OSA) and frailty is still limited.
Objective: To determine the association between the older adults who had a high-risk of OSA and adverse events including frailty, cognitive frailty, quality of life, history of admission within previous year and history falling within previous 6 months.
Materials and Methods: A cross-sectional study was conducted between October 1, 2019 to January 31, 2022, at Srinagarind Hospital, Thailand. Participants aged ≥60 years who visited outpatient of internal medicine department were included. The Thai Frailty Index (TFI) was used to evaluate frailty status. STOP-BANG questionnaire was used to evaluate the risk of OSA and a score ≥3 was defined as a high-risk of OSA. The demographic data, TFI, the Thai version of the World Health Organization Quality of Life Brief–Old and Montreal Cognitive Assessment (MoCA) were obtained. The association between the older adults who had a high-risk of OSA and adverse events was analyzed by multiple logistic regression and presented as adjusted odds ratio (aOR) with 95% confidence interval (CI).
Results: A total of 198 participants were included. The older adults who had a high-risk of OSA was 124 (62.6%). The older adults who had a high-risk of OSA were associated with frailty (aOR of 3.37, 95% CI 1.56 to 7.71, p-value=0.003). The older adults who had a high-risk of OSA were not associated with cognitive frailty, fair quality of life, history of admission within previous year and falling within previous 6 months.
Conclusion: The older adults who had a high-risk of OSA were associated with frailty. The screening and diagnosis of OSA are recommended for the older adults who attend the outpatient clinic.

DOI:10.35755/jmedassocthai.2023.S01.13761

Keywords : Frailty; High-risk of OSA; Older adults


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