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Short-Term Neonatal Morbidities Associated with Early Term Births

Rachaporn Rattanamalee¹, Pracha Nuntnarumit²

Affiliation : ¹ Specific Medical System Section, Medical Services Division, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; ² Division of Neonatology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

Abstract
Objective: To determine short-term morbidities of infants born at early term gestation.
Materials and Methods: A medical chart review was conducted to compare the data between early term at 37 to 38⁺⁶ weeks of gestation and full term neonates at 39 to 40⁺⁶ weeks of gestation born between January 1, 2018 and December 31, 2021 at Ramathibodi Hospital, Mahidol University, Thailand. The primary and secondary outcomes were short-term respiratory and non-respiratory morbidities of early term neonates, respectively.
Results: One thousand eight hundred neonates were recruited, 900 were early term and 900 were full term neonates. Overall, early term neonates were 44.3% spontaneous births and 23.5% elective cesarean sections. Early term neonates had significantly increased risk of respiratory morbidities, including delayed transitional period (p<0.001), transient desaturation (p=0.038), transient tachypnea of the newborns (p<0.001), and requirement of oxygen supplementation (p<0.001). Early term neonates also had significantly higher non-respiratory morbidities than those of full term neonates, including hypothermia (p<0.001), hypoglycemia (p=0.003), jaundice requiring phototherapy (p=0.004), septic evaluations (p<0.001), admission to a special care nursery (p<0.001), total length of stays (p<0.001), and readmission (p=0.018).
Conclusion: Early term neonates had significantly increased risk of short-term respiratory and non-respiratory morbidities. Avoidance of early term delivery should be performed to prevent morbidities related to early term births.

Received 28 February 2024 | Revised 13 June 2024 | Accepted 19 June 2024
DOI: 10.35755/jmedassocthai.2024.8.14020

Keywords : Early term neonates; Early term births; Neonatal morbidities


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