NK/T Cell Lymphoma, Nasal Type with Sinonasal Mass and Palatal Ulcer: A Clinical Case Report and Review of Treatment

Nonglak Kanitsap MD*, Naree Warnnissorn MD**

Affiliation : * Division of Hematology, Department of Medicine, Faculty of Medicine, Thammasat University, Rungsit Campus, Pathumtani, Thailand ** Department of Pathology, Faculty of Medicine, Thammasat University, Rungsit Campus, Pathumtani, Thailand

Extranodal Nasal NK/T cell lymphoma, relatively uncommon type of non-Hodgkin’s lymphoma, is highly aggressive disease with poor outcomes. Early stage disease may response to radiotherapy alone. However the treatments are usually chemotherapy and radiotherapy combination and late stage disease may not response to any available therapy. We reported a 45-year-old woman with extranodal nasal type NK/T cell lymphoma. The patient presented with chronic nasal stuffiness and mucous bloody discharge. The nasal mass is extensively involved periorbital and sinonasal soft tissue. Due to the extensively involved of tumor, combination chemotherapy was used to induce response. This patient was involved by complicated infection and palatal ulcer with likely perforation. The salvage chemotherapy was given and the treatment of NK/T cell lymphoma from other reports and literatures were reviewed.

Keywords : Lymphoma, NK/T cell, Nasal type

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