Detection of Bacterial Antigen in Cerebrospinal Fluid in Patients with Baterial Meningitis: A Literature Review

Somporn Srifuengfung PhD*, Kulkunya Chokephaibulkit MD**

Affiliation : * Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ** Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Rapid detection of bacterial pathogen causing meningitis is very important to guide antimicrobial therapy before the standard culture result is available. Other than gram stain, one of the most useful rapid methods is the detection of bacterial antigen in cerebrospinal fluid. This article reviewed the methods of bacterial antigen detection for diagnosis of meningitis as well as a microbiology aspect of this life-threatening disease.

Keywords : Detection, Bacterial antigen, CSF, Bacterial meningitis

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