Incidence, Mortality Rate and Rate of Thrombolytic Therapy of Acute Stroke in Northeastern Thailand from 2017-2022
Pattranit Songsrichainun1, Somsak Tiamkao1,2
Affiliation : 1 Division of Neurology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 Integrated Epilepsy Research Group, Khon Kaen University, Khon Kaen, Thailand
Background: Stroke is a true medical emergency condition with thrombolytic treatment with recombinant tissue plasminogen activator as the standard treatment. In Thailand, including the Northeast region (Health region 7 to 10), stroke incidence and mortality rate have increased. However, there is no study of stroke incidence, recombinant tissue plasminogen activator (rtPA) access rate, and mortality rate by district in Northeastern Thailand.
Objective: This study aimed to present stroke incidence, access rate of thrombolytic treatment, and acute stroke mortality rates for each district in Northeast Thailand for the 5 years, 2017 to 2022.
Materials and Methods: The study drew from the Thai National Health Security Office’s (NHSO) database for 2017 to 2022 and reported using rates per 100,000 population and percentage statistics.
Results: The overall incidence of acute stroke and acute ischemic stroke patients aged over 15 years in Northeastern Thailand were 264.19 to 331.70/100,000 population and 184.57 to 232.82/100,000 population respectively. The rtPA access rate was 6.09 to 8.01% (Main Universal Coverage Scheme) and 6.01 to 7.92% (Referral Universal Coverage Scheme). The mortality rate of acute ischemic stroke patients within 30 days and post-rtPA were 8.80 to 10.43% and 3.65 to 5.67% respectively.
Conclusion: In Northeastern Thailand, stroke incidence has shown an upward trend over the past 5 years. The number of acute ischemic stroke patients receiving rtPA has also been on the rise. The mortality rate in patients with acute ischemic stroke within 30 days declined from 2017 to 2019, then increased from 2020 to 2022. Particularly notable was the increase in the mortality rate among patients with acute ischemic stroke post-intravenous thrombolysis.
Received 30 January 2024 | Revised 9 July 2024 | Accepted 16 July 2024
DOI: 10.35755/jmedassocthai.2024.S01.S16-S23
Keywords : Incidence; Mortality rate; Stroke; Thrombolytic drug; Northeastern Thailand
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