Exploring Potentially Inappropriate Medications for Elderly Thai Patients in an Outpatient Setting at a Tertiary Care Hospital: an Analysis Based on the 2023 American Geriatrics Society Beers Criteria
Tippayavadee Wannawichate1, Manchumad Manjavong2, Panita Limpawattana2
Affiliation : 1 Department of Pharmacy Service, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 Internal Medicine Department, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Objective: Potentially Inappropriate Medications (PIMs) in older patients are prevalent and possess the potential for modification. It is linked to several detrimental health outcomes. The extent of research pertaining to PIMs in Thailand remains restricted. The primary aim of the present study was to determine the prevalence of PIMs, employing the Beers criteria from 2023. The secondary objective focused on the identification of factors correlated with PIMs within this population.
Materials and Methods: A retrospective electronic medical record of older patients at outpatient clinics of Srinagarind Hospital during November 2021 and November 2022 was reviewed. Patient demographic data were collected and analyzed. The Beers criteria (version 2023) were employed for identifying PIMs. Logistic regression analysis was used to determine contributing to the occurrence of PIMs.
Results: Of the 23,758 patients enrolled, 49.03% were found to have at least one PIM. The factors that exhibited associations were age (odds ratio [OR] 1.01), polypharmacy (≥5 medications) (OR 6.29), dementia (OR 1.84), osteoarthritis (OR 1.40), chronic kidney disease (OR 1.29), hypertension (OR 1.15), dyslipidemia (OR 0.87), diabetes mellitus (OR 0.84), gastritis/gastrointestinal reflux disease/peptic ulcer disease (OR 0.59), and peripheral vascular disease (OR 0.29).
Conclusion: The present study highlights the high prevalence of PIMs among elderly outpatients. Factors associated with PIMs were identified, it is possible to develop and implement targeted strategies aimed at reducing the use of PIMs in order to mitigate the negative clinical consequences associated with PIMs in these populations.
Received 18 January 2024 | Revised 22 March 2024 | Accepted 1 April 2024
DOI: 10.35755/jmedassocthai.2024.S01.S1-S8
Keywords : Beers criteria; Older adults; Elderly; Outpatient; Potential inappropriate
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