Handling Uncertainty of the Economic Evaluation Result: Sensitivity Analysis

Supon Limwattananon MPHM, PhD*

Affiliation : * Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen

An economic evaluation of health technology and interventions often comes with uncertainty in the parameters that were used in the model. To determine sensitivity of the result obtained from a reference case analysis, researchers can employ deterministic and probabilistic approaches. This methodological guideline summarizes the principles underlying the sensitivity analysis and recommends that the probabilistic sensitivity analysis is the best method to handle the parameter uncertainty.

Keywords : Acceptability curve, Monte Carlo simulation, Sensitivity analysis, Tornado diagram

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