Measurement of Clinical Effects

Yot Teerawattananon MD, PhD*, Montarat Thavorncharoensap PhD*,**, Adun Mohara MSc*

Affiliation : * Health Intervention and Technology Assessment Program, Ministry of Public Health, Nonthaburi ** Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok

The measurement and valuation of clinical effects is a significant component of economic evaluation. Decision makers are commonly interested in how a particular health intervention works in everyday practice; therefore, the resulting outcome under this circumstance is called the effectiveness. Clinical effects usually measure final intended effects of a proposed health technology in terms of the ultimate change in health state brought about by the technology. The systematic review and meta-analysis of high quality RCTs is the most favorable method to synthesize evidence because they are disciplined and transparent methods. The present chapter focuses on how to make a valid measure of clinical effects for use in cost-effectiveness analysis and how clinical effect is to be appropriately defined and measured.

Keywords : Clinical effects, Clinical evidence, Measure, Effectiveness

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