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Case Report: of Multiple Intermittent Urticaria After
Treatment of COVID-19 Infection
Naphat Bhumiratana MD¹, Thanan Supasiri MD, MPH² , ³, Nuntida Salakshna MD¹ , ⁴, Wilai Thanasarnaksorn MD¹ , ⁵
Affiliation : ¹ Samitivej Esthetics Institute, Samitivej Sukhumvit Hospital, Bangkok, Thailand ² Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand ³ Life Center, Samitivej Sukhumvit Hospital, Bangkok, Thailand ⁴ Science Division, Mahidol University International College, Bangkok, Thailand ⁵ Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
The authors report a case of a 32-year-old Thai woman with a COVID-19 infection that presented with urticaria and angioedema with a pityriasis
rosea (PR)-like rash at a private hospital in Thailand. She presented at the hospital with bloody nasal discharge and diarrhea but without fever,
myalgia, or any respiratory symptoms. She complained of angioedema and PR-like lesions on the third day of the treatment. Urticarial rash
appeared intermittently for four weeks after all medications were discontinued, during which the patient had no fever, no respiratory symptoms,
or any other symptoms. However, the RT-PCR results for COVID-19 RNA were positive during the time that the urticarial symptoms persisted. The
COVID-19 RNA became negative on the fourth day after the last urticarial episode. Urticarial rash may be a clue that the inflammatory process is
activated by COVID-19 virus after the treatment is completed.
Received 9 March 2021 | Revised 10 June 2021 | Accepted 15 June 2021
doi.org/10.35755/jmedassocthai.2021.07.12420
Keywords :
Cutaneous; Pityriasis rosea; Angioedema; Urticaria; COVID-19
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