The Effects of Mindfulness and Self-Compassion-Based
Group Therapy for Major Depressive Disorder:
A Randomized Controlled Trial
Chanikan Anuwatgasem, MD¹, Tantawan Awirutworakul, MD², Sakda Arj-Ong Vallibhakara, MD, PhD³,
Porntip Kaisa-ard, RN¹, Thidarat Yamnim, RN¹, Kamonwan Phadermphol, RN¹, Pissamai Pranudta, PN¹,
Pattara Wisajun, MSc¹, Sudawan Jullagate, BA¹
Affiliation : ¹ Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand ² Chakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand ³ ASEAN Institute for Health Development, Mahidol University, Nakhon Pathom, Thailand
Objective: To find the influences of mindfulness and self-compassion-based group therapy and compare them with standard
treatment outcomes.
Materials and Methods: Prospective randomized control trial was conducted on two intervention groups (n=23 for mindfulness and self-compassion group, n=11 for the control group) for seven weeks. Depression-related parameters consisted of the Montgomery-Åsberg Depression Rating Scale (MADRS) Thai version, Self-Compassion scale-Thai version (Thai-SCS), Pittsburgh Sleep Quality Index-Thai version (Thai-PSQI), Hospital Anxiety and Depression Scale-Thai version (Thai-HADS), Thai-Perceived Stress Scale-10 (T-PSS-10), Rosenberg self-esteem Thai version, and the World Health Organization Quality of Life (WHOQOL) Thai version, were collected and compared before and after both treatments.
Results: Mindfulness and self-compassion had statistically significant improvement of better depressive rating scale, anxiety, mindfulness & self-compassion, perceived stress scale, self-esteem, and quality of life (p<0.001, 0.001, 0.002, <0.001, 0.005 and <0.001, respectively). Depressive level, anxiety level, mindfulness, and self-compassion, perceived stress scale, self-esteem, and quality of life in both groups were also improved. Nonetheless, there were no significant differences when compared to the mean differences between both groups.
Conclusion: Mindfulness and self-compassion intervention improved depression, anxiety, stress, self-esteem, and quality of life.
Received 5 August 2020 | Revised 15 August 2020 | Accepted 5 September 2020
doi.org/10.35755/jmedassocthai.2020.09.12020
Keywords : Mindfulness and self-compassion therapy, Group psychotherapy, Depression, Thai-MADRS, Thai-SCS, Thai-PSQI,
Thai-HADS, T-PSS-10, Thai- WHOQOL, Thai-Rosenberg self-esteem, Thai-SCS
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