Endocervical Histopathology Specimen Adequacy in Fractional Curettage

Chongcharoen P, MD¹, Chinthakanan O, MD, MPH¹

Affiliation : ¹ Department of Obstetrics and Gynaecology, Faculty of Medicine, Ramathibodi Hospital,Mahidol University, Bangkok, Thailand

Objective: To evaluate the adequacy of endocervical histopathology specimen from fractional curettage (FC) and impact of clinical factors.
Materials and Methods: A retrospective descriptive study involving women underwent FCs gathering normal cervical cytology in Ramathibodi Hospital between January 2012 and December 2016.
Results: Three hundred eighty-seven participants underwent FC. The indications of FC were 58.4% pre-menopausal abnormal uterine bleeding, 31% post-menopausal bleeding, 10.6% other indications. The overall adequacy of endocervical specimens obtained by endocervical curettage (ECC) was 45.5%, which was higher in pre-menopausal group [48.0% pre-menopause versus 40.9% post-menopause, OR 0.74 (95% CI 0.49 to 1.14)]. There were no statistically significant differences in adequacy of ECC specimens with respect to baseline characteristics. Pathological report of one patient indicated malignancy from both endometrial tissue and ECC (0.2%). The complications rate was 1.3% from procedure and anesthetic complication.
Conclusion: ECC provided 45.5% adequacy in women with normal cervical cytology. There was no identified clinical risk factor regarding adequate endocervical specimens.

Keywords : Fractional and curettage, Endocervical curettage, Abnormal uterine bleeding, Specimen adequacy

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