Concurrent Tuberculoma of Medulla Oblongata and Tuberculosis of Bone Marrow: A First
Case Report: and Literature Review

Jiranukool J, MD¹, Thiarawat P, MD¹

Affiliation : ¹ Department of Neurosurgery, Naresuan University, Phitsanulok, Thailand

The authors reported a first case of concurrent tuberculoma of medulla oblongata and tuberculosis of bone marrow. The patient presented with vertigo, vomiting, and headache for two months. Magnetic resonance imaging (MRI) showed irregular ring enhancing lesion at medulla and magnetic resonance spectroscopy (MRS) showed increased lipid peak in central area of lesion. The patient’s diagnosis was tuberculoma. In addition, bone marrow biopsy was done because of leukocytosis and thrombocytosis. The pathological results showed granulomatous inflammation and positive polymerase chain reaction (PCR) for Mycobacterium tuberculosis complex. The patient was treated with anti-tuberculous drugs for 18 months, and MRI follow-up revealed disappearance of the lesions, including clinical improvement.

Keywords : Tuberculoma, Tuberculosis, Medulla oblongata, Bone marrow

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