Cronkhite-Canada Syndrome: The First Case Series in Thai Population
Mati Chuamanochan MD1, Napatra Tovanabutra MD1, Pongsak Mahanupab MD2, Sarawut Kongkarnka MD2, Siri Chiewchanvit MD1
Affiliation : 1 Division of Dermatology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand 2 Department of Pathology, Chiang Mai University, Chiang Mai, Thailand
The authors reported three Thai patients diagnosed with Cronkhite-Canada Syndrome [CCS]. All patients presented with chronic diarrhea resulting from gastrointestinal [GI] polyposis and the characteristic cutaneous (cid:976)indings, hyperpigmented skin, nail dystrophy, and/or hair loss. CCS is uncommon worldwide, with only one previously reported case from Thailand. To the authors knowledge, this was the (cid:976)irst case series of Thai CCS patients. In the present report, the authors summarized the epidemiologic and clinical information of the Thai patients and compared them to the data from other countries. The frequency of each cutaneous (cid:976)inding and the histologic type of the polyps differed between Thai patients and other ethnic groups.
Keywords : Cronkhite-Canada syndrome, First case series, Thai population
