Comparison of Biodegradable Polymer Biolimus A9 Eluting
Stents versus Durable Biocompatible Polymer Everolimus
Eluting Stents in the Treatment of Coronary Bifurcation
Lesions
Rattanachai Chanchai MD1, Pannipa Suwannasom MD, PhD1,2, Tasalak Thonghong MD1, Noparat Thanachaikun MD1,
Srun Kuanprasert MD1
Affiliation :
1 Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
2 North Region Heart Center, Maharaj Nakorn Chiang Mai Hospital, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Objective : To compare the long-term clinical outcomes between biodegradable polymer-coated biolimus A9-eluting stent [BES]
and durable biocompatible polymer-coated everolimus-eluting stent [EES] in the treatment of bifurcation lesions according to
Thailand’s universal coverage scheme.
Materials and Methods : The authors retrospective reviewed bifurcation lesions treated either with BES or EES in their institution
between January 2010 and December 2015. The incidence of target vessel failure [TVF] (a composite of cardiac death, myocardial
infarction [MI], and target vessel revascularization [TVR]) in (cid:976)ive years were compared between the two groups.
Results : One hundred sixty bifurcation lesions treated with BES in 84 lesions and EES in 76 lesions were analyzed. Patient and
procedural characteristics were comparable between the two groups. One stent strategy was performed in similar proportion
between the two platforms (BES 81% versus EES 75%, p = 0.44). There were no statistically signi(cid:976)icant differences in TVF rates
between the two groups (BES 11.9% versus EES 14.5%, p = 0.75). The incidence of TVR (BES 6.0% versus EES 3.9%, p = 0.72) and
stent thrombosis [ST] (BES 1.2% versus EES 1.3%, p = 1.00) were comparable between the two groups.
Conclusion : The long-term clinical outcomes in the treatment of coronary bifurcation lesions under Thailand’s universal coverage
scheme was comparable between BES and EES. There was a comparable rate of ST irrespective of the types of polymer.
Keywords : Biolimus-eluting stent, Everolimus-eluting stent, Coronary bifurcation
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