The Effect of Extracorporeal Circulation and Cross-
Clamping Period on Erectile Dysfunction in Cardiac
Surgical Patients: One-Year Follow-Up Study
Surakarn Saraithong MD1, Warin Pongkankham MD2, Pote Aimpun MD, PhD3, Kriengchai Prasongsukarn MD, MSc1
Affiliation :
1 Division of Cardiovascular Thoracic Surgery, Department of Surgery, Phramongkutklao Hospital, Bangkok, Thailand
2 Department of Naval Medicine, Royal Thai Navy, Somdejprapinklao Hospital, Bangkok, Thailand
3 Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand
Background : Erectile dysfunction [ED] can impact the quality of life. Thus, it is crucial to know the erectile function in patients
who underwent cardiac surgery.
Objective : To investigate the factors in(cid:976)luencing ED in the patients with cardiac surgery.
Materials and Methods : A one-year follow-up study of patients that underwent cardiopulmonary bypass [CPB] in Phramongkutklao
Hospital was conducted. A self-administered questionnaire including International Index of Erectile Function [IIEF]-5 was provided
and collected at preoperative, 6-, and 12-month postoperative periods. Discrete variables were analyzed by Chi-square test and
continuous variables were analyzed by paired or unpaired t-test. Statistical signi(cid:976)icance was de(cid:976)ined as p-value lower than 0.05.
Results : Three hundred thirty-three males (mean age 58.0±14.2) were enrolled. Of these, the procedures were performed as
follow, 45% CABG, 6% CABG with valvular heart surgery, 41% valvular heart surgery, 3% congenital heart surgery, and 5% others.
The prevalence of ED signi(cid:976)icantly decreased after the operation with the prevalence of 91.6%, 84.1%, and 79.5% at preoperative,
6-, and 12-month postoperative periods, respectively (p<0.001). The IIEF-5 score was signi(cid:976)icantly increased from 11.9±7.5
preoperatively to 12.7±7.9 and 13.2±8.3 at 6- and 12-month postoperative periods, respectively (p<0.05). Advanced age, smoking,
alcohol consumption, hypertension, diabetes mellitus, chronic kidney disease, and β-blocker use were risk factors associated with
ED. In contrast, the CPB and the aortic cross-clamping period were not associated with ED.
Conclusion : ED prevalence decreased after cardiac surgery possibly resulting from the improvement of the cardiac function and
psychological and physical status after surgery.
Keywords : ED, Cardiac surgery, IIEF-5, CPB, Thailand
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