Proportion of Thai Patients with Atrial Fibrillation Receiving Warfarin with Labile INR in Each Group of SAMeTT2R2 Score

Komsing Methavigul MD, FRCPT1

Affiliation : 1 Department of Cardiology, Central Chest Institute of Thailand, Nonthaburi, Thailand

Objective : To determine the proportion of Thai AF patients used warfarin with labile INR in each SAMeTT2R2 score.
Materials and Methods : The present retrospective study recruited Thai atrial (cid:976)ibrillation [AF] patients treated at the Central Chest Institute of Thailand. They took warfarin for at least three months before enrollment. The patients that discontinued warfarin during the international normalized ratio [INR] monitoring because of surgery, invasive procedure, hospitalization, or any etiologies were excluded. Each AF patients was measured for the INR to determine the proportion of patients with labile INR in each SAMeTT2R2 score.
Results : Forty AF patients were enrolled. The mean age was 64.35±10.69 years old. Most patients were paroxysmal AF. The average CHA2DS2-VASc score was 3.20±1.56. Half of these patients had hypertension and hypercholesterolemia. Almost one-(cid:976)ifth of these patients had history of ischemic stroke. The study showed the increased proportion of AF patients with labile INR according to the increased SAMeTT2R2 score. The AF patients with SAMeTT2R2 score of 3 or more had a closer proportion of patients with labile INR than those with SAMeTT2R2 score of 2 or less with borderline signi(cid:976)icance (p-value 0.056).
Conclusion : Thai AF patients with increased SAMeTT2R2 score had potential of having labile INR. However, a larger study is needed to use SAMeTT2R2 score for predicting Thai AF patients with labile INR in the future.

Keywords : Atrial (cid:976)ibrillation, Bleeding risk score, Anticoagulant, Labile INR, SAMeTT2R2

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