Wisa Anegmudchalin MD*, Kamol Panumatrassamee MD*, Apirak Santi-ngamkun MD*
Affiliation : * Division of Urology, Department of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Background : Intraabdominal carbon dioxide following laparoscopic adrenalectomy results in postoperative shoulder tip 
pain. Several interventions to reduce this pain have been used, but were not so effective.
Objective : To evaluate the efficacy of soft silicone drain in reducing shoulder tip pain after laparoscopic adrenalectomy.
Material  and  Method:  A  prospective  randomized  control  trial  was  done  on  38  patients  undergoing  laparoscopic 
adrenalectomy and randomized prospectively into two groups in King Chulalongkorn Memorial Hospital, Bangkok, Thailand. 
In  our  previous  observational  study,  we  collected  data  of  pain  scores  from  two  patient  groups  after  laparoscopic 
adrenalectomy. There were five cases with soft silicone drains and five cases without soft silicone drains. We found that 
those with drains had significantly decreased mean pain score. In this study, the patients were divided into two groups. 
Patients in group A (n = 19) underwent laparoscopic adrenalectomy with soft silicone drains and patients in group B           
(n = 19) underwent laparoscopic adrenalectomy without soft silicone drains. Shoulder-tip pain was recorded on a visual 
analogue scale (VAS) at 4, 8, 12, 24, and 48 hours after operation. The quantity of analgesics required by the patients were 
recorded on the first and second day postoperatively.
Results : Twelve patients in group A (63.2%) and 14 patients in group B (73.68%) complained of shoulder-tip pain. However, 
there  was  no  significant  difference  in  the  frequency  and  intensity  of  shoulder-tip  pain  between  groups  A  and  B.  The 
postoperative shoulder-tip pain scores were not significantly different between the groups. The quantity of analgesics required 
by the patients in the two groups were not significantly different. According to VAS, pain scores were found to be highest at 
the fourth and the eighth hours postoperatively. The trends were similar in both groups.
Conclusion : Although our previous observational studies found that drains help reducing shoulder tip pain, our present 
randomized control trial found that they could not significantly reduce shoulder tip pain. Further studies to reduce shoulder 
tip pain should be conducted.
Keywords : Shoulder tip pain, Soft silicone drain, Analgesic drug, Laparoscopy, Adrenalectomy
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