Reversible Cerebral Vasoconstriction Syndrome:
A Report on Three Cases
Duangnapa Roongpiboonsopit MD, MSc*,
Kannikar Kongbunkiat MD, MSc**,***, Kammant Phanthumchinda MD****
Affiliation :
* Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand
** Division of Neurology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
*** North-eastern Stroke Research Group, Khon Kaen University, Khon Kaen, Thailand
**** Division of Neurology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital,
Chulalongkorn University, Bangkok, Thailand
Reversible cerebral vasoconstriction syndrome (RCVS), a recently recognized syndrome, is defined as an intermittent
segmental vasospasm of cerebral arteries accompanied by thunderclap headache. The major complications of RCVS include
ischemic or hemorrhagic stroke, which may cause morbidity and mortality. It is important to detect RCVS in clinical practice
because misdiagnosis may lead to inappropriate treatment. In Thailand, there are only two reported cases of RCVS, which
may reflect an underdiagnosis of this syndrome. To raise awareness of RCVS, we reported a case series of three RCVS cases.
Two of the presented cases had interesting precipitating factors, and two cases had an unusual delayed clinical course.
Keywords : Reversible cerebral vasoconstriction syndrome, Thunderclap headache, Herbal supplements, Biologically
fermented juice
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