Oral Candida Colonization in Thai Patients with Psoriasis
Leena Chularojanamontri MD*, Chanisada Wongpraparut MD*, Papapit Tuchinda MD*,
Waranaree Winayanuwattikun MD*, Adhiratha Boonyasiri MD**, Kanokvalai Kulthanan MD*, Visanu Thamlikitkul MD***
Affiliation :
* Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
** Division of Clinical Epidemiology, Department of Research and Development, Faculty of Medicine Siriraj Hospital,
Mahidol University, Bangkok, Thailand
*** Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital,
Mahidol University, Bangkok, Thailand
Objective : To investigate the prevalence and risk factors of oral Candida colonization in psoriatic patients at Siriraj Hospital.
Material and Method: Sixty patients with psoriasis, aged older than 18 years, were recruited for the study group. Sixty
healthy individuals similar to the patients in the study group in terms of age and gender were recruited for the control group.
Candida spp. was isolated from oral swabs and oral rinses taken from all subjects.
Results : During the study period, 27 (45.0%) psoriatic patients used only topical treatment and the remaining patients were
on systemic treatment. Oral Candida colonization was significantly higher in patients with psoriasis (30%), as compared
with healthy controls (13.3%). Candida albicans was the predominant Candida species isolated. Presence of oral candidiasis
was significantly associated with systemic treatment.
Conclusion : Oral Candida colonization is associated with psoriasis, especially in patients who receive systemic treatment.
Keywords : Candida, Colonization, Psoriasis
All Articles
Download