Characteristics and Outcomes of Treatment for
Non-ST-Segment Elevation Acute Coronary Syndrome:
Results from a Single Center Registry
Satchana Pumprueg MD*, Warangkna Boonyapisit MD*,
Jareethip Wongsa RN**, Nongnuch Naekaew RN**, Daranee Decha RN**
Affiliation :
* Division of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital,
Mahidol University, Bangkok, Thailand
** Department of Nursing, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Background : Acute coronary syndrome (ACS) is a leading health burden worldwide. The Siriraj non-ST-segment elevation
acute coronary syndrome (NSTE-ACS) registry was established in 2012. Here, we report in-hospital outcomes and one-year
outcomes from patients in the registry.
Objective : To investigate and report characteristics and outcomes of treatment for NSTE-ACS at one year from a single
center.
Material and Method: All patients admitted to Siriraj Hospital with diagnosis of NSTE-ACS were enrolled. Baseline
demographic information, presenting signs and symptoms, electrocardiogram, and blood chemistry were recorded.
In-hospital complications and outcomes of treatment were also collected and recorded. After being discharged from the
hospital, patients were followed-up for one year.
Results : Two-hundred patients were evaluated between January 2012 and August 2013. A majority of patients (65.5%)
presented with angina. Median TIMI risk score was 4. Thirty-two percent of patients had GRACE risk score greater than
140. In-hospital mortality was 3.5% (95% CI 2.0-7.0). The most common complication was heart failure (36.5%).
Three patients had CVA during admission. At one year, the mortality rate was 5% (95% CI 3.0-9.0). Unplanned readmission
rate was 9.5%.
Conclusion : Most patients in the registry were high-risk ACS patients. In-hospital mortality and one-year mortality rates
were 3.5% and 5%, respectively. Results from this study were comparable to results reported by previous studies from the
Western world.
Keywords : Non-ST-segment elevation acute coronary syndrome, NSTE-ACS, outcomes, Thailand
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