Natthawut Phothong MD*,**, Thawatchai Akaraviputh MD*, Vitoon Chinswangwatanakul MD*, Asada Methasate MD*, Atthaphorn Trakarnsanga MD*
Affiliation : * Minimally Invasive Unit, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ** Department of Surgery, Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University, Nonthaburi, Thailand
Objective : To demonstrate potential benefits of three-port hand-assisted laparoscopic sigmoidectomy (HALS) compared 
with open sigmoidectomy (OS) in terms of short-term outcomes and cost-benefit.
Material and Method: A retrospective review of a database of cases that matched 100 sigmoid cancer patients treated with 
sigmoidectomy at the Department of Surgery, Siriraj Hospital was performed. Short-term outcomes and costs of treatment 
were collected and analyzed.
Results :  There  were  no  differences  in  age,  gender,  body  mass  index,  American  Society  of  Anesthesiologists’  score,           
Charlson comorbidity index score, and previous surgery between OS and HALS groups. The three-port HALS group had 
significantly less blood loss (50 (5-400) mL vs. 120 (10-1,000) mL, p<0.001), faster time to regular diet (64.620.7 hours 
vs. 97.652.5 hours, p<0.001), and lower pain score (4.31.7 vs. 5.31.6, p = 0.008). The hospital-stay related cost was 
significantly lower in HALS group ($114 ($47-$789) vs. $190 ($57-$1,462), p<0.001). The low rate of infection was a major 
contributory factor (12% vs. 0%, p = 0.03). This was further emphasized in subgroup analysis of surgical site infection 
(SSI). While there are great benefits, the operative cost is higher in HALS. However, there is no significant difference in 
total costs of OS and HALS (US $2,243 ($1,321-$5,241) vs. $1,942 ($1,427-$11,910), p = 0.054).
Conclusion : Simplified three-port HALS can be successfully performed with superior short-term outcomes and preserved 
oncologic outcomes. Cost-benefit advantage was highlighted especially in the area of high rate of SSI.
Keywords : Hand-assisted laparoscopic sigmoidectomy, Short-term outcomes, Cost analysis
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