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Correlation between Retinal Nerve Fiber Layer Thickness and Central Corneal Thickness in Healthy Subjects

Duangdao Thatsnarong MD*

Affiliation : * Department of Ophthalmology, Mettapracharak Hospital, Nakhon Pathom, Thailand.


Objective : To evaluate the correlation between retinal nerve fiber layer (RNFL) thickness obtained by optical coherence tomography (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany) and central corneal thickness (CCT) in healthy subjects. Material and Method: This was a retrospective cross-sectional study. Two hundred twenty nine healthy subjects were included in the present study. All subjects received a standard ocular examination, including RNFL thickness measurement by optical coherence tomography. CCT measurement was performed by ultrasonic pachymeter. The Pearson’s correlation test was used to determine the relationship between CCT and RNFL thickness.
Results : The significantly positive relationship was found between CCT and RNFL thickness in overall average and inferior sector. There was no statistically significant relationship found between CCT and the other sectors of RNFL thickness.
Conclusion : CCT was statistically significant related to RNFL thickness in overall average and inferior sector in healthy subjects.

Keywords : Central corneal thickness, Retinal nerve fiber layer thickness


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MEDICAL ASSOCIATION OF THAILAND
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