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Primary Intrarenal/Perirenal Neuroblastoma Mimicking Wilms’ Tumor at Presentation in a 5-Year-Old Girl: A Case Report from Siriraj Hospital

Jitsupa Treetipsatit MD*, Kanapon Pradniwat MD*, Mongkol Laohapensang MD**, Chantima Rongviriyapanich MD***, Kamon Phuakpet MD****, Kleebsabai Sanpakit MD****

Affiliation : * Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ** Division of Pediatric Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand *** Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand **** Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Primary intrarenal/perirenal neuroblastoma (NB) is NB that primarily arises in intrarenal and/or perirenal regions. Regarding its location, this tumor can mimic Wilms’ tumor, a more common pediatric renal tumor, at presentation. Owing to difference in clinical management and prognosis, it is crucial to distinguish primary intrarenal/perirenal NB from Wilms’ tumor at the time of diagnosis. Recognition of its characteristic features, which are distinctive from its adrenal counterpart, is helpful to guide to the correct diagnosis and proper treatment. However, due to its rarity with less than 100 cases described in English literatures, the characteristics of primary intrarenal/perirenal NB have not been widely studied. The authors, therefore, report this case of primary intrarenal/perirenal NB, which occurred in right kidney of a 5-year-old Thai girl in order to illustrate the characteristic features of this tumor. To the authors’ knowledge, this case is the first case of primary intrarenal/perirenal NB that has been reported in Thailand.

Keywords : Neuroblastoma, Intrarenal neuroblastoma, Perirenal neuroblastoma


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