The Treatment Outcome of Radical Radiotherapy in Laryngeal Cancer
Imjai Chitapanarux MD*, Ekkasit Tharavichitkul MD*, Somvilai Chakrabandhu MD*, Pitchayaponne Klunklin MD*, Wimrak Onchan MD*, Nantaka Pukanhapan RN*, Jirawattana Srikawin RN*, Pichit Sittitrai MD**, Roy Vongtama MD***
Affiliation : * Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand ** Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand *** St. Teresa Comprehensive Cancer Center, Stockton, California, USA
Objective : This study reports the treatment outcome of radiotherapy alone for laryngeal cancer.
Material and Method: A retrospective analysis was performed on 138 patients with stage I to IV squamous cell carcinoma
of larynx who received radiotherapy alone in Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang
Mai University, Thailand between 2003 and 2009.
Results : The 4-year local control (LC) rate in all patients was 44.1%. The 4-year overall survival (OS) was 82.1%. The
4-year LC rates for stage I, II, III, and IV were 75.3%, 69.4%, 57.1%, and 36.9%,respectively (p = 0.0055). Finally, the
4-year OS rates for stage I, II, III, and IV were 85%, 78.6%, 91.1%, and 71.5%, respectively. The laryngeal preservation
rate of all stages was 73%.
Conclusion : In conclusion, the treatment outcome of radiotherapy alone in all stages of laryngeal cancer in our center was
unsatisfactory when compared to other series.
Keywords : Laryngeal cancer, Radiotherapy alone, Outcome
