A Comparison of Vestibular Evoked Myogenic Potential
(VEMP) between Definite Meniere’s Disease Patients
and Normal Healthy Adults
Chanchai Jariengprasert MD*,
Montip Tiensuwan PhD**, Khongpol Euasirirattanapaisan MSc***
Affiliation :
* Department of Otolaryngology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
** Department of Statistics, Faculty of Sciences, Mahidol University, Bangkok, Thailand
*** Audiologist, Private Practice, Department of Otolaryngology, Faculty of Medicine, Ramathibodi Hospital,
Mahidol University, Bangkok, Thailand
Objective : To compare the results of VEMP between unilateral definite Meniere’s disease patients and normal healthy adults.
Material and Method: Thirty-two patients with unilateral definite Meniere’s disease patients and 32 age-matched normal
healthy adults (control) underwent VEMP tests with short tone burst of 500 Hz at 90 dBnHL. Student-t test was used for
comparison of means of all parameters between two groups.
Results : Absent VEMP response was found in 14 MD patients and abnormal asymmetry ratio (AR) was found in five MD
patients. Normal responses were found in all subjects of the control group. The mean P1 and N1 latencies, VEMP amplitude
between unilateral MD, and control were not significantly different between two groups. However, the difference between
the mean AR of both groups showed statistically significant (p-value <0.05). The upper limit of normal AR was calculated
to be of 35.15%.
Conclusion : The absence of VEMP response and AR of VEMP were more dominant than other parameters such as P1 and
N1 latencies or VEMP amplitude in the detection of saccular dysfunction in MD. The results suggested that AR should be
used as a tool in interpretation of VEMP response for the diagnostic batteries in MD. The upper limit of normal AR of
≤35% should be recommended.
Keywords : Vestibular evoked myogenic potential (VEMP), Meniere’s disease, Asymmetry ratio
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