Autologous Chondrocyte Implantation for Cartilage
Injury Treatment in Chiang Mai University Hospital:
A Case Report
Prasit Wongtriratanachai MD*, Dumnoensun Pruksakorn MD, PhD*, Peraphan Pothacharoen PhD**,
Puwapong Nimkingratana MD*, Nuttaya Pattamapaspong MD***, Chanakarn Phornphutkul MD*,
Sasiwariya Setsitthakun MNS****, Ladda Fongsatitkul MSc*****, Sureeporn Phrompaet MSc*
Affiliation :
* Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
** Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
*** Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
**** Operative Unit, Chiang Mai University Hospital, Chiang Mai, Thailand
***** Blood Bank Unit, Chiang Mai University Hospital, Chiang Mai, Thailand
Autologous chondrocyte implantation (ACI) has become one of the standard procedures for articular cartilage
defect treatment. This technique provides a promising result. However, the procedural process requires an approach of
several steps from multidisciplinary teams. Although the success of this procedure has been reported from Srinakharinvirot
University since 2007, the application of ACI is still limited in Thailand due to the complexity of processes and stringent
quality control. This report is to present the first case of the cartilage defect treatment using the first generation-ACI under
Chiang Mai University’s (CMU) own facility and Ethics Committee. This paper also reviews the process of biotechnology
procedures, patient selection, surgical, and rehabilitation techniques. The success of the first case is an important milestone
for the further development of the CMU Human Translational Research Laboratory in near future.
Keywords : Autologous chondrocyte implantation, Cartilage defect, Treatment
All Articles
Download