Fever, Skin Rash, Jaundice and Lymphadenopathy after Trichloroethylene Exposure : A Case Report
THIRABHATRA CHITT ASOBHAKTRA, M.D.*, PENPUN WATTANAKRAI, M.D.**, ABHASSANEE SOHONSLITDSUK, M.D.***, WIN AI WANNANUKUL, M.D.*, CHUTIMA PRAMOOLSINSAP, M.D.***, PRAWAT NITIYANANT,M.D.****
Affiliation : * Department of Medicine, ** Division of Dermatology, *** Division of Gastroenterology & Tropical Medicine, Department of Medicine, **** Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Abstract Trichloroethylene, a chlorinated hydrocarbon has been reported to cause many adverse health effects. This paper describes a female patient presenting with rather unusual manifestation secondary to trichloroethylene (TCE) exposure, i.e. hepatitis and generalized dermatitis. The diagnosis was confirmed by positive skin patch testing with 50 per cent TCE solution. After with- drawal from the exposure site, her symptoms improved and liver function test returned to baseline level after a three-months period of follow-up. TCE induced immunologic reaction has been postulated as the pathological process of this illness.
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