Anti-E as a Cause of Hemolytic Disease of the Newborn
RUANGRONG CHEEPSATTAYAKORN, M.D.*, SOMPORN CHOTINARUEMOL, M.D.***, LADDA FONGSATITKUL, M.Sc. **, METIRA MAHA WONGTONG, B.Sc. **
Affiliation : * Department of Pathology, ** Blood Transfusion Service, *** Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Abstract A case of HDN caused by anti-E antibody is reported. A group A, E-positive, hemoglobin E trait female infant was born from a group A, E-negative, B-thalassemia I hemoglobin E mother. Hyperbilirubinemia was noted at the first day of life. The DAT was positive. Anti-E was detected in the maternal serum. Jaundice and anemia occurring to the baby were severe enough to require phototherapy intervention for 9 days and 50 ml of group A, E-negative packed red blood cells was transfused. The baby's condition improved. She was discharged at 12 days of age. Follow-up of the baby at 1 year old showed that she was alive and in good health.
Keywords :
