Castleman's Disease : A Clinicopathologic Study of 12 Cases
VIRA KASANTIKUL,M.D.*, VORANUT PANYAVORAVUT,M.D.*, SUNPETCH BENJA VONGKULCHAI, M.D.*, VIRATT PANICHABHONGSE, M.D.**
Affiliation : * Department of Pathology, Faculty of Medicine, Chulalongkom University, Bangkok 10330, ** Department of Surgery, Bangkok General Hospital, Bangkok 10110, Thailand.
Abstract Castleman's disease observed in 12 Thai patients was investigated. The male to female ratio was I : 3. Peak prevalence was in the third and fourth decades. It is suggested that the disease in Orientals tends to have extrathoracic mass more often than in Caucasians. Solitary non-tender slow growing mass was the most common symptom. Generalized lymphadenopathy in associa- tion with cutaneous plasmocytoma was noted in one example while asymptamatic pelvic lesion in a patient was discovered incidentally. Histologically, the hyaline-vascular type was found in 8 instances, the remainders were plasma-cell type. Surgery was effective for localized lesions while systemic form could benefit from chemotherapy.
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