A Comparison of the Effects of Oral and Percutaneous Oestradiol on the Lipid Profile and on Atheroma For- mation
C.J. Haines*, N. Panesar*, A.E. James*, T.J. Ngai*, D.S. Sahota*, R.L. Jones*
Affiliation : * The Prince of Wales Hospital, The Chinese University of Hong Kong, New Territories, Hong Kong.
After 12 weeks there were significant increases in the concentrations of TC in all groups. There was no significant difference in TC concentrations between the 3 groups. There was a highly significant reduction in atheroma formation in Groups 2 and 3 compared with Group I. These results suggest both oral and percutaneous oestradiol have a direct protective effect on the cardiovascular system independent of serum concentrations of total cholesterol.
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