Anti Ro/SSA Positive Undifferentiated Connective Tissue Disease Mother with a Newborn with Complete Congenital Heart Block: A Case Reportt
WORAWIT LOUTHRENOO, M.D.*, REKWAN SITTIWANGKUL, M.D.**, SUMAN AS BOONYARATA VEJ, M.D.*, WARAPORN SUKITAWUT, B.Sc.*
Affiliation : * Division of Rheumatology, Department of Medicine, ** Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. t Presented at the annual meeting of the Royal College of Physicians of Thailand, Lotus Pang Suan Kaew Hotel, Chiang Mai, 22-25 Aprill997
Abstract An associatiOn between complete congenital heart block (CCHB) and anti-Ro/SSA antibody is well recognized but has never been reported in Thailand. We report here a 37-year-old female who was admitted because of massive epistaxis secondary to immune thrombocytopenia. She had given birth to a child with CCHB 2 years previously, when she was healthy. Antinuclear antibody and anti-Ro/SSA were positive in her sera, but were negative in her son. The relation- ship between anti-Ro/SSA antibody and outcome of mothers with infants with CCHB is reviewed.
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