Thyroid Scintigraphy in Children with Hypothyroidism: A Five-year Experiencet
PAWANA PUSUWAN,M.D.*, SUTTIPONG WACHARASINDHU, M.D.**, VIYADA ATTANATHO, M.D.*, SUPA WADEE LIKITMASKUL, M.D.**, SOMLAK INTARASUPHT, M.Sc. *, JIRAPORN MUNGKHARAK, M.D.*, RUDEE PLEEHACHINDA, M.D.* SUNANTA CHIEWVIT, M.D.*,
Affiliation : *Department of Radiology, ** Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. t Presented at the Scientific Meeting of the Nuclear Medicine Society of Thailand, Bangkok, November, 1996.
Abstract The presence or absence of thyroid glandular tissue demonstrated by thyroid scintigraphy is important for genetic and prognostic counseling and for acceleration of diagnosis in other affected siblings. Technetium-99m-pertechnetate thyroid scintigraphy was performed on 27 children with cretinism at the Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital during the 5-year period from June 1991. Based on scintigraphic findings, three main groups of thyroid localization were seen. Thirteen ( 48.1%) were athyrotic while 3 (11.1%) had an ectopic thyroid and 11 (40.8%) had gland in normal position. Perchlorate discharge test was performed in 8 children of the last group and the results were positive indicating an organification defect. Thyroid scintigraphy and perchlorate discharge test provided the useful information for diagnosis, follow-up, and prognosis in children with cretinism.
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