Methotrexate Induced Pericarditis and Pericardia} Effusion in Psoristic Patient
PRANEE PALUNGWACHIRA, M.D.*, PITI PALUNGWACHIRA, M.D.**, PIBOON LAOHATHAI, M.D.***
Affiliation : * Family Medicine Department, Ramathibodi Hospital, Mahidol University, Bangkok 10400, ** Skin Center, Srinakharinwirot University, Bangkok 10110, *** Intensive Care Unit, Samitivej Hospital, Bangkok 10310, Thailand.
Abstract We describe a 62-year-old woman with Psoriasis who presented as Methotrexate - induced pericarditis and pericardia! effusion. Aspiration of the pericardium was required and the patient made a satisfactory recovery. At six - months follow-up, she remained well, psoriasis plaques was controlled by topical crude coal tar and topical corticosteroid. These complications are extremely rare, but have been described as isolated phenomena associated with methotrexate therapy.
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