Nonadherence in Thberculosis Treatment Among HIV Patients Attending Bamrasnaradura Hospital, Nonthaburi
SOMSIT TANSUPHASAWADIKUL, B.Sc., M.D.*, DAGMARA MAGDALENA POPRAWSKI, M.B.B.S., D.T.M. & H., M.C.T.M.**, PUNNEE PITISUTTITHUM, M.B.B.S, D.T.M. & H., F.R.C.T.P.*** BENJALUCK PHONRA T, M.Sc. ***
Affiliation : * Bamrasnaradura Hospital, Ministry of Public Health, Nonthaburi 11000, ** Department of Defence- Army in Townsville, Australia. *** Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Abstract
Objective : To determine the clinical manifestations, outcome and nonadherence, in tuber-
culosis (TB) among HIV patients in Bamrasnaradura Hospital, Nonthaburi.
Design : A retrospective cohort study; hospital record files were reviewed over ll months.
A total of 200 consecutive HIV patients were entered and followed for a 6 months period of
their TB treatment. Sociodemographic data, symptoms and signs and results of investigation
tests were recorded at the time of presentation, while diagnosis, and clinical outcome were done
at the end of the follow-up time.
Results : Extrapulmonary tuberculosis (58%) was more common than pure pulmonary
involvement (42%). Lymphadenopathy (52%) was the commonest sign on physical examination.
Chest X-rays were positive in 55 per cent cases, while AFB examination was positive in 48.5 per
cent from the sputum and 46 per cent from lymph node aspirate specimens. After 6 months of
treatment, 30 per cent patients were still alive, 12 per cent had died, and 50 per cent were lost to
follow-up. Factors such as low socioeconomic status (p Keywords :
