Combined Raw Cornstarch and Nifedipine as an Addi- tional Treatment in Persistent Hyperinsulinemic Hypo- glycemia of Infancy

CHITTIWAT SUPRASONGSIN, M.D.*, PAT MAHACHOKLERTWATTANA, M.D.**, UMAPORN SUTHUTVORAVUT, M.D.**, CHAWALIT PREEYASOMBAT,M.D.**

Affiliation : * Research Center, ** Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok !0400, Thailand.

AbstractThis study reports the result of treatment with the combination of raw cornstarch and nifedipine in two infants affected with hyperinsulinemic hypoglycemia of variable severity. The first infant developed hypoglycemia during early neonatal period and required subtotal pancrea- tectomy. She still developed hypoglycemia after her second operation. The second infant developed hypoglycemia at the age of 7 months. Raw cornstarch and nifedipine efficiently normalized both infants' blood glucose levels. Although they still need frequent feedings, no hypo- glycemic episode was reported except when they were sick. Their growth and development were markedly improved after initiation of treatment.

Keywords : Persistent Hyperinsulinemic Hypoglycemia of Infancy, Raw Cornstarch, Nifedipine, Treatment

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