Anti-P : The Most Common Unexpected Antibodies in Northeastern-Thais

AMORNRAT V ROMPHRUK,M.Sc.*, JONGKOL AKAHAT, M.Sc.*, THORNGMUK ANUPHAN, Cert in Med Lab.*, CHINTANA PUAPAIROJ, M.D.* CHALAWAN WANHAGIJ, B.Sc.*, PUTHIDA T ANTANAPORNKUL, B.Sc. *, PRAMUAL PATTAYASO, B.Ed.*,

Affiliation : * Blood Transfusion Centre, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

AbstractThe prevalence of unexpected antibodies in the Northeastern-Thai population was studied. Sera were collected from 25,673 blood donors including 18,209 males and 7,464 females. The sera were screened for unexpected antibodies by saline and enzyme techniques. The sera which gave a positive antibody screening test were identified for specificity of antibody. The result demon- strated that 3,928 from 25,673 samples (15.30%) were positive for the antibody screening test and only 3,883 samples could be identified for specificity of antibody. The most common unex- pected antibodies were anti- P1, anti- lewis and anti- P1 +anti- lewis with the frequency of 70.8, 18.6 and 10.1 per cent, respectively. The prevalence of anti-P1 in this study was higher than that reported in Central Thailand and Southeast Asia which may due to the high prevalence of liver fluke infection in the Northeastern-Thai population.

Keywords : Anti-P1, Unexpected Antibody

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