Pregnancy Outcomes of Mothers with Very Advanced
Maternal Age (40 Years or More)
Kuntharee Traisrisilp MD*,
Theera Tongsong MD*
Affiliation :
* Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Objective : To assess pregnancy outcomes in women at age of 40 years or more compared with those at age of 20 to 30 years.
Material and Method: The retrospective cohort study was conducted at Maternal Fetal Medicine Unit, Chiang Mai University,
Thailand, to identify the delivery. All consecutive records between January 2002 and December 2012 were searched.
Singleton pregnancies with maternal age of 20 years or older were recruited for study. The primary outcomes for comparison
were the rates of various obstetric outcomes, such as preterm birth, cesarean section, etc.
Results : During the study period, 797 women at age of 40 years or more and 18,802 women at age of between 20 and
30 years were recruited. Women in the study group had significantly higher rates of medical diseases, such as chronic
hypertension or pregestational diabetes mellitus. Cesarean rate, preterm delivery, and fetal growth restriction were
significantly higher in the study group.
Conclusion : Maternal age of 40 years or more is associated with medical complications and more operative deliveries.
Furthermore, very advanced maternal age is significantly associated with adverse perinatal outcomes such as abortion,
preterm birth, and fetal growth restriction. This information may be useful for obstetric counseling.
Keywords : Very advanced maternal age, Age at or more than 40 years, Pregnancy outcome
All Articles
Download