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Original ArticleOpen Access
Tissue Imprint for Intra-operative Evaluation of Musculoskeletal Tumors
Wisanuyotin T 
,
Mitchai J ,
Sirichativapee W ,
Kosuwon W ,
Sumnanoont C ,
Jeeravipoolvarn P
,
Mitchai J ,
Sirichativapee W ,
Kosuwon W ,
Sumnanoont C ,
Jeeravipoolvarn P Objective: To evaluate the usefulness of an intra-operative tissue imprint as a role to provide a provisional
diagnosis in patients with musculoskeletal tumors.
Material and Method: 118 patients underwent surgical treatment for musculoskeletal tumors. Tissue imprints
from suspected tissues were conducted in all of the patients and the results were compared with the final
permanent section.
Results: The usefulness of the imprint slides (i.e., the diagnostic yield) was 88.14%. The respective, overall
sensitivity, specificity, accuracy, positive and negative predictive value was 93.75%, 100%, 96.15%, 100%
and 90.90%.
Conclusion: Tissue imprinting is a useful method for intra-operative evaluation of adequacy and provides a
provisional diagnosis of the musculoskeletal tumors lesions.
Keywords: Bone neoplasms, Cytodiagnosis, Musculoskeletal tumors, Intra-operative period
diagnosis in patients with musculoskeletal tumors.
Material and Method: 118 patients underwent surgical treatment for musculoskeletal tumors. Tissue imprints
from suspected tissues were conducted in all of the patients and the results were compared with the final
permanent section.
Results: The usefulness of the imprint slides (i.e., the diagnostic yield) was 88.14%. The respective, overall
sensitivity, specificity, accuracy, positive and negative predictive value was 93.75%, 100%, 96.15%, 100%
and 90.90%.
Conclusion: Tissue imprinting is a useful method for intra-operative evaluation of adequacy and provides a
provisional diagnosis of the musculoskeletal tumors lesions.
Keywords: Bone neoplasms, Cytodiagnosis, Musculoskeletal tumors, Intra-operative period
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