Material and Method: The association between LV systolic function and in-hospital mortality in 2,427 patients undergoing PCI included in TPCIR between May and October 2006, was studied. Patients were categorized as either left ventricular ejection fraction (LVEF) less than 40% or LVEF 40% or more.

Results: In-hospital mortality was 8.0% among patients with LVEF less than 40% and 1.3% in those with LVEF of 40% or more. After adjustment for baseline variables, those associated with increased hospital mortality were, LVEF less than 40% (OR = 2.87, 95% CI = 1.57 to 5.23), p<0.001, history of heart failure (OR = 15.99, 95% CI = 8.10 to 31.56, p<0.001), previous stroke (OR = 66.96, 95% CI = 11.01 to 407.36, p<0.001), and extent of coronary artery disease (OR = 2.12, 95% CI = 1.04 to 4.32, p = 0.038).

Conclusion: The results of the present study suggest that LV systolic function, and history of heart failure within two weeks may increase in-hospital mortality following PCI in unselected patients and across all indications for PCI. Assessing LV function before PCI appears warranted.

Keywords: PCI, Left ventricular systolic function