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Original ArticleOpen Access
A “See and Treat” Approach for High Grade Squamous Intraepithelial Lesion on Cervical Cytology
Charoenkwan K 
,
Srisomboon J ,
Siriaunkgul S ,
Khunamornpong S ,
Suprasert P ,
Phongnarisorn C ,
Siriaree S ,
Cheewakriangkrai C
,
Srisomboon J ,
Siriaunkgul S ,
Khunamornpong S ,
Suprasert P ,
Phongnarisorn C ,
Siriaree S ,
Cheewakriangkrai C Objective: To examine the final histologic findings as well as to correlate colposcopic and histologic findings in patients who had a high-grade squamous intraepithelial lesion (HGSIL) on the Pap smear and underwent colposcopy followed by LEEP on the “See and Treat” basis without intervening colposcopically directed biopsy.
Material and Method: The medical records of patients with HGSIL on cytology who underwent LEEP without prior cervical biopsy at Chiang Mai University Hospital over a 5-month period were reviewed. The authors summarized the final LEEP histologic results and correlated colposcopic and histologic findings in these patients.
Results: Of 55 patients who had a see-and-treat LEEP, 53 patients (96%) had a high-grade intraepithelial lesion or higher. There were 11 patients (20%) who had invasive squamous cell carcinoma. Of 4 patients with a low-grade lesion on colposcopic examination, all had a high-grade lesion or higher on final histology. Forty-four patients (96%) with high-grade impression on colposcopy had high-grade or more severe lesion on the final histologic diagnosis.
Conclusion: For patients with a high-grade lesion on the Pap smear, LEEP according to the “See and Treat”
approach appeared to be a reasonable alternative to conventional colposcopically directed biopsy, especially
in low resource settings.
Keywords: Cervical neoplasia, Colposcopy, High-grade squamous intraepithelial lesion, Large loop excision
of the transformation zone, Loop electrosurgical excision procedure
Material and Method: The medical records of patients with HGSIL on cytology who underwent LEEP without prior cervical biopsy at Chiang Mai University Hospital over a 5-month period were reviewed. The authors summarized the final LEEP histologic results and correlated colposcopic and histologic findings in these patients.
Results: Of 55 patients who had a see-and-treat LEEP, 53 patients (96%) had a high-grade intraepithelial lesion or higher. There were 11 patients (20%) who had invasive squamous cell carcinoma. Of 4 patients with a low-grade lesion on colposcopic examination, all had a high-grade lesion or higher on final histology. Forty-four patients (96%) with high-grade impression on colposcopy had high-grade or more severe lesion on the final histologic diagnosis.
Conclusion: For patients with a high-grade lesion on the Pap smear, LEEP according to the “See and Treat”
approach appeared to be a reasonable alternative to conventional colposcopically directed biopsy, especially
in low resource settings.
Keywords: Cervical neoplasia, Colposcopy, High-grade squamous intraepithelial lesion, Large loop excision
of the transformation zone, Loop electrosurgical excision procedure
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