J Med Assoc Thai 2002; 85 (12):1288

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The Risk and Effectiveness of Transurethral Resection of Prostate
Lertakyamanee J Mail, Ruksamanee E , Tantiwong A , Boonsuk K , Nilpradab l , Soontrapa S

Background
: To advise a patient to have transurethral resection of prostate (TURP) needs
information on the benefit and complications of the procedure. Quality assurance also needs present
results to be compared with future ones.
Objectives
: The authors wanted to know: 1. Whether TURP can decrease the International
prostate symptom score (IPSS) and improve the Quality of Life (QOL) scores concerning urination
at 1.5 months post-operatively for at least 25 per cent of the pre-operative scores? ; 2. What are the
common medical diseases in this type of patient? ; and 3. What are the mortality and immediate
complications of TURP?
Method
: This was a prospective, before-after design trial. All patients who came to have
TURP at a tertiary care hospital were studied. IPSS and QOL scores were recorded before surgery and
again when the patients came back to follow up at 1.5 months after discharge. Patients were evaluated
for cardiopulmonary reserve and congestive heart failure. Anesthetic technique of choice was spinal
anesthesia with 0.5 per cent bupivacaine. Anesthetic and surgical complications were recorded if the
definitions were met.
Analysis
: Pre-operative and 1.5 months post-operative scores were compared using paired
t-test and 95 per cent confidence interval.
Results:
During the 13 months there were 269 consecutive males who received TURP. The
mean
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SD age was 70.4
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8.8 years (range 35-97). The mean difference between pre-and post-opera-
tive IPSS was 6.7
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9.1 (95% CI 5.2-7.8). Quality of Life also improved, the mean difference between
pre-and post-operative QOL was 3.2
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1.6 (95% CI 2.9-3.5). Most patients had ASA class 2. Com-
mon pre-operative existing diseases were hypertension (31.6%), ischemic heart disease (18.2%), dia-
betes (15.6%), and COPD (7.1%). Anesthetic techniques were spinal block (77.3%), epidural block
Vol. 85 No.l2
THE RISK AND EFFECTIVENESS OF TRANSURETHRAL RESECTION OF PROSTATE
1289
(5.9% ), continuous epidural ( 11.2% ), and general anesthesia (5.6% ). Intra-operative complications
were reported and TUR syndrome occurred in I patient (0.37%). There was one surgical death 3 days
post-operation, due to septic shock probably from bowel perforation.
Conclusion : The patients' symptoms and quality of life significantly improved, but there
was 1 surgical death and 1 TUR syndrome among 269.
Key word : TURP
LERTAKYAMANEE

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