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Original ArticleOpen Access
Risk Factors for Pseudomonas aeruginosa Bacteremia in Thai Patients
SOMPORN SANTIPRASITKUL, M.Sc. **,
VISANU THAMLIKITKUL, M.D.****
A case control study to determine the risk factors for
P. aeruginosa
bacteremia was con-
ducted in patients admitted to Siriraj Hospital in 1998.
The case group consisted of 65 patients with
P. aeruginosa
bacteremia. There were 3 con-
trol groups. 65 patients with
E.
coli
bacteremia, 64 patients with
S. aureus
bacteremia and 65 patients
without bacteremia. Demographic information and potential risk factors i.e. type of infection, asso-
ciated diseases/conditions, procedures/surgery, previous/current use of antibiotics and previous/current
use of immunosuppressive/cytotoxic agents were extracted from the patients' medical records and
compared. Univariate analysis revealed that the factors associated with
P. aeruginosa
bacteremia
were infections acquired while hospitalized, hematologic malignancy, neutropenia, COPD, antibiotic
receivers, cytotoxic agents receivers. However, multivariate analysis revealed that only hematologic
malignancy, infections acquired while hospitalized and previous use of parenteral antibiotics were risk
factors for
P. aeruginosa
bacteremia.
Key word :
Pseudomonas aeruginosa
Bacteremia, Risk Factor
VISANU THAMLIKITKUL, M.D.****
A case control study to determine the risk factors for
P. aeruginosa
bacteremia was con-
ducted in patients admitted to Siriraj Hospital in 1998.
The case group consisted of 65 patients with
P. aeruginosa
bacteremia. There were 3 con-
trol groups. 65 patients with
E.
coli
bacteremia, 64 patients with
S. aureus
bacteremia and 65 patients
without bacteremia. Demographic information and potential risk factors i.e. type of infection, asso-
ciated diseases/conditions, procedures/surgery, previous/current use of antibiotics and previous/current
use of immunosuppressive/cytotoxic agents were extracted from the patients' medical records and
compared. Univariate analysis revealed that the factors associated with
P. aeruginosa
bacteremia
were infections acquired while hospitalized, hematologic malignancy, neutropenia, COPD, antibiotic
receivers, cytotoxic agents receivers. However, multivariate analysis revealed that only hematologic
malignancy, infections acquired while hospitalized and previous use of parenteral antibiotics were risk
factors for
P. aeruginosa
bacteremia.
Key word :
Pseudomonas aeruginosa
Bacteremia, Risk Factor
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