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Case ReportOpen Access
Solitary Keratoacanthoma of the Conjunctiva : Report of a Case
Tulvatana W 
,
Pisamkorskul P ,
Wannakrairot P
,
Pisamkorskul P ,
Wannakrairot P Keratoacanthoma characteristically occurs on the skin and is rarely found in the conjunc-
tiva. We, herein, report a case of a healthy 41-year-old Thai woman presenting with a rapidly grow-
ing conjunctival mass. The tumor was excised to exclude squamous cell carcinoma. Histopatho-
logy revealed a cup shaped well-circumscribed proliferation of squamous cells, with a central
keratin crater, consistent with a keratoacanthoma. On the literature review, only 12 cases have pre-
viously been reported in the English language. The mean age of presentation was 40.75 years, with
a male preponderance. Presentation of a mass was mostly within 4 weeks after onset. History of
foreign material getting into the eye was positive in 5 cases. All cases were successfully treated by
excision, except for one case in which malignancy transformation was found, and enucleation was
required eventually.
Conjunctival keratoacanthoma is a rare disease. However, this lesion should be well recog-
nized and not misinterpreted as malignancy. As far as we are aware, this is the first report of con-
junctival keratoacanthoma from this region.
Key word : Keratoacanthoma, Conjunctiva, Squamous Cell Carcinoma
tiva. We, herein, report a case of a healthy 41-year-old Thai woman presenting with a rapidly grow-
ing conjunctival mass. The tumor was excised to exclude squamous cell carcinoma. Histopatho-
logy revealed a cup shaped well-circumscribed proliferation of squamous cells, with a central
keratin crater, consistent with a keratoacanthoma. On the literature review, only 12 cases have pre-
viously been reported in the English language. The mean age of presentation was 40.75 years, with
a male preponderance. Presentation of a mass was mostly within 4 weeks after onset. History of
foreign material getting into the eye was positive in 5 cases. All cases were successfully treated by
excision, except for one case in which malignancy transformation was found, and enucleation was
required eventually.
Conjunctival keratoacanthoma is a rare disease. However, this lesion should be well recog-
nized and not misinterpreted as malignancy. As far as we are aware, this is the first report of con-
junctival keratoacanthoma from this region.
Key word : Keratoacanthoma, Conjunctiva, Squamous Cell Carcinoma
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