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Original ArticleOpen Access
Correlation of Oocyte Morphology with Fertilization Rate and Embryo Quality After Intracytoplasmic Sperm Injection
Suppinyopong S 
,
Choavaratana R ,
Karavakul C
,
Choavaratana R ,
Karavakul C SUWIT SUPPINYOPONG, M.D.*,
ROUNGSIN CHOA V ARATANA, M.D.*
CHARUNEE KARA VAKUL, B.Ed.*,
To determine whether the morphology of the oocyte assessed under light microscopy is
related to the results of intracytoplasmic sperm injection (ICSI). 135 ICSI oocytes from 15 patients
were analyzed. Transvaginal ultrasound -guided oocytes retrieval with oocyte morphology
evaluation based on shape of the first polar body and perivitelline space followed by ICSI. After
48 hours, embryo quality was evaluated and compared to each pre-injected oocyte morphology.
Normal fertilization was achieved in 81.5 per cent of the oocytes ( 110/135 ). Abnormal fertili-
zation (3 pronuclei) was 1.5 per cent (2/135). Fertilization rate of oocytes with good morpho-
logy was higher than those with poor morphology, but there was no statistical significance
(82.4%
vs
79.5%; p
>
0.05). Oocytes with good morphology were significantly fertilized to be
embryos with good quality (p
<
0.001). This study suggests that oocyte morphology correlates
with embryo quality after ICSI.
Key word : Oocyte Morphology, Fertilization, Embryo Quality, Intracytoplasmic Sperm Injection
ROUNGSIN CHOA V ARATANA, M.D.*
CHARUNEE KARA VAKUL, B.Ed.*,
To determine whether the morphology of the oocyte assessed under light microscopy is
related to the results of intracytoplasmic sperm injection (ICSI). 135 ICSI oocytes from 15 patients
were analyzed. Transvaginal ultrasound -guided oocytes retrieval with oocyte morphology
evaluation based on shape of the first polar body and perivitelline space followed by ICSI. After
48 hours, embryo quality was evaluated and compared to each pre-injected oocyte morphology.
Normal fertilization was achieved in 81.5 per cent of the oocytes ( 110/135 ). Abnormal fertili-
zation (3 pronuclei) was 1.5 per cent (2/135). Fertilization rate of oocytes with good morpho-
logy was higher than those with poor morphology, but there was no statistical significance
(82.4%
vs
79.5%; p
>
0.05). Oocytes with good morphology were significantly fertilized to be
embryos with good quality (p
<
0.001). This study suggests that oocyte morphology correlates
with embryo quality after ICSI.
Key word : Oocyte Morphology, Fertilization, Embryo Quality, Intracytoplasmic Sperm Injection
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