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Case ReportOpen Access
Fine Needle Aspiration Cytology of Metastatic Transitional Cell Carcinoma to the Liver
Kanjanavirojkul N 
,
Kularbkaew C ,
Yutanawiboonchai W
,
Kularbkaew C ,
Yutanawiboonchai W A 63-year-old man presented with a three-month history of painless hematuria. A cysto-
scopic examination revealed a diffuse small nodulopapillary growth of the bladder mucosa. Biopsy
resulted in the diagnosis of a transitional cell carcinoma (TCC), grade II. Therefore, total cystec-
tomy with an ileal conduit was performed and the pathologic examination demonstrated a TCC
grade !VIII apparently confined to the mucosa. However, an ultrasonographic study carried out
one year later revealed tumor masses in the pelvic cavity and the liver. FNA and needle biopsy of
the liver were carried out and the diagnosis of a metastatic TCC was made from the former. Needle
biopsy results pointed to a metastatic undifferentiated carcinoma, most likely originating from
the TCC. The advantage of FNA is discussed. It is being used with increasing frequency to diag-
nose mass lesions in the liver and can identify metastatic tumors which have specific cytologic
features that are different from primary liver tumor.
Key word
: Fine Needle Aspiration, Cytology, Transitional Cell Carcinoma, Metastatic, Liver
scopic examination revealed a diffuse small nodulopapillary growth of the bladder mucosa. Biopsy
resulted in the diagnosis of a transitional cell carcinoma (TCC), grade II. Therefore, total cystec-
tomy with an ileal conduit was performed and the pathologic examination demonstrated a TCC
grade !VIII apparently confined to the mucosa. However, an ultrasonographic study carried out
one year later revealed tumor masses in the pelvic cavity and the liver. FNA and needle biopsy of
the liver were carried out and the diagnosis of a metastatic TCC was made from the former. Needle
biopsy results pointed to a metastatic undifferentiated carcinoma, most likely originating from
the TCC. The advantage of FNA is discussed. It is being used with increasing frequency to diag-
nose mass lesions in the liver and can identify metastatic tumors which have specific cytologic
features that are different from primary liver tumor.
Key word
: Fine Needle Aspiration, Cytology, Transitional Cell Carcinoma, Metastatic, Liver
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