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Original ArticleOpen Access
Cyanide Poisoning, 2 Cases Report and Treatment Review
Ruangkanchanasetr S 
,
Wananukul V ,
Suwanjutha S
,
Wananukul V ,
Suwanjutha S Two patients, a 4-year-old girl and her brother 1 1/2 year-old, with cyanide poisoning are
reported. They vomited and became comatose 9 hours after ingestion of boiled cassava. At a
community hospital, they were intubated and given ventilatory support. The girl was transferred
to Ramathibodi Intensive Care Unit. At 19 hours after ingestion, sodium nitrite and sodium thiosulfate
were given as well as other supportive treatment. She recovered with normal breathing on
the next day. The boy was referred to Ramathibodi 4 hours later. On arrival, he appeared normal
except for the bitter almond breathe. Only supportive treatment was given. Their blood cyanide
levels on arrival were 0.56 and 0.32 11g/ml (normal value < 0.3 11g/ml) respectively confirming
the diagnosis of cyanide poisoning. Other abnormal laboratory findings included metabolic
acidosis and lactic acidemia.
The pathogenesis and management of cyanide poisoning are reviewed.
Key word : Cyanide Poisoning, Cassava Ingestion
reported. They vomited and became comatose 9 hours after ingestion of boiled cassava. At a
community hospital, they were intubated and given ventilatory support. The girl was transferred
to Ramathibodi Intensive Care Unit. At 19 hours after ingestion, sodium nitrite and sodium thiosulfate
were given as well as other supportive treatment. She recovered with normal breathing on
the next day. The boy was referred to Ramathibodi 4 hours later. On arrival, he appeared normal
except for the bitter almond breathe. Only supportive treatment was given. Their blood cyanide
levels on arrival were 0.56 and 0.32 11g/ml (normal value < 0.3 11g/ml) respectively confirming
the diagnosis of cyanide poisoning. Other abnormal laboratory findings included metabolic
acidosis and lactic acidemia.
The pathogenesis and management of cyanide poisoning are reviewed.
Key word : Cyanide Poisoning, Cassava Ingestion
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