J Med Assoc Thai 1999; 82 (4):352

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Skin Thickness in Different Menopausal Status
Panrakhamlerd K Mail, Chotnopparatpattara P , Kukulprasong A , Chaikittisilpa S , Limpaphavom K

It is well known that skin thickness will decrease in the years after menopause. Women
may have climacteric symptoms including those associated with skin alterations as early as
during the perimenopausal period. This study was performed to compare the skin thickness of
women in their premenopause (N=31), perimenopause (N=35) and early postmenopause (N=46).
The mean skin thickness in each group was 2.28 ± 0.39 mm., 2.18 ± 0.35 mm. and 2.02 ± 0.36
mm. respectively. The skin thickness of women in the early postmenopausal group was significantly
lower than those in the premenopausal group, but no difference was found between premenopausal
and perimenopausal group nor between perimenopausal and early postmenopausal
group. Furthermore, we found no correlation between skin thickness and chronological age. In
conclusion, the decline in skin thickness of women entering menopause requires a period of time to
undergo significant alterations and the study revealed a significant reduction of skin thickness
as early as in the course of the early postmenopausal period.
Key word : Menopause, Skin Thickness

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