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Original ArticleOpen Access
The Effect of Standardized Ginseng Extract on Peripheral Blood Leukocytes and Lymphocyte Subsets: A Preliminary Study in Young Healthy Adults
Srisurapanon S 
,
Rungroeng K ,
Apibal S ,
Cherdrugsi P ,
Siripol R ,
Vanichangkul V ,
Timvipark C
,
Rungroeng K ,
Apibal S ,
Cherdrugsi P ,
Siripol R ,
Vanichangkul V ,
Timvipark C The present study was undertaken in twenty young, healthy Thai males to investigate the
effects of prolonged administration of standardized ginseng extract on peripheral blood leukocytes
and lymphocyte subsets. The subjects were divided into two equal groups as ginseng and placebo
groups. The first group received two capsules daily of standardized ginseng extract 150 mg per
capsule for 8 weeks. The second group received placebo and served as control. Circulatory levels
of total and differential leukocyte counts and percentage of lymphocyte subsets were determined
prior to and at the 4th and 8th week of the experimental period. There were no significant differences
in the total and differential leukocyte counts as well as the lymphocyte subpopulations:
CD3 (T cells), CD 19 (B cells), CD4 (T-helper cells), CD8 (T-suppression cells), CD4/CD8 ratio,
and CD25 (lnterleukin-2-receptor cells) between the two subject groups throughout the experimental
period. We concluded that oral administration of standardized ginseng extract, 300 mg/day
for 8 weeks caused no significant changes in peripheral blood leukocytes and lymphocyte subsets
in young, healthy Thai males.
effects of prolonged administration of standardized ginseng extract on peripheral blood leukocytes
and lymphocyte subsets. The subjects were divided into two equal groups as ginseng and placebo
groups. The first group received two capsules daily of standardized ginseng extract 150 mg per
capsule for 8 weeks. The second group received placebo and served as control. Circulatory levels
of total and differential leukocyte counts and percentage of lymphocyte subsets were determined
prior to and at the 4th and 8th week of the experimental period. There were no significant differences
in the total and differential leukocyte counts as well as the lymphocyte subpopulations:
CD3 (T cells), CD 19 (B cells), CD4 (T-helper cells), CD8 (T-suppression cells), CD4/CD8 ratio,
and CD25 (lnterleukin-2-receptor cells) between the two subject groups throughout the experimental
period. We concluded that oral administration of standardized ginseng extract, 300 mg/day
for 8 weeks caused no significant changes in peripheral blood leukocytes and lymphocyte subsets
in young, healthy Thai males.
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