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Case ReportOpen Access
Bilateral Atypical Femoral Fractures after Long-Term Alendronate Therapy: A Case Report
Bamrungsong T 
,
Pongchaiyakul C
,
Pongchaiyakul C Bisphosphonates therapy has been shown to decrease the risk of vertebral, non-vertebral, and hip fractures in
postmenopausal women. However, the long-term safety of bisphosphonates use has been questioned. Recent reports have
demonstrated the association between long-term alendronate therapy with low-energy subtrochanteric fracture or diaphyseal
femoral fractures in a small number of patients. The author reported the first case of bilateral atypical femoral fractures in
postmenopausal women with osteoporosis receiving long-term alendronate therapy.
Keywords: Atypical, Femoral fracture, Bisphosphonates, Alendronate
postmenopausal women. However, the long-term safety of bisphosphonates use has been questioned. Recent reports have
demonstrated the association between long-term alendronate therapy with low-energy subtrochanteric fracture or diaphyseal
femoral fractures in a small number of patients. The author reported the first case of bilateral atypical femoral fractures in
postmenopausal women with osteoporosis receiving long-term alendronate therapy.
Keywords: Atypical, Femoral fracture, Bisphosphonates, Alendronate
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