Recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) is a rare disease characterized by clinical features of pruritic purpuric papules and angioedema. Skin biopsies revealed the eosinophil-predominate necrotizing vasculitis affecting small dermal vessels. Systemic corticosteroid is a very effective treatment. There are many side effects associated with systemic corticosteroid therapy. The authors report a case of RCNEV successfully treated with indomethacin. To the authors’ knowledge, there has been no reported case of RCNEV treated with indomethacin.

Keywords: Indomethacin, Recurrent cutaneous necrotizing eosinophilic vasculitis, Treatment